Recommendations for Hepatitis B Immunoglobulin and Antiviral Prophylaxis Against Hepatitis B Recurrence After Liver Transplantation
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info:eu-repo/semantics/openAccessTarih
2021Yazar
Mesut AkarsuSoner Onem
Ilker Turan
Gupse Adali
Meral Akdogan
Murat Akyildiz
Murat Aladag
Yasemin Balaban
Nilay Danis
Murat Dayangac
Genco Gencdal
Hale Gokcan
Elif Sertesen
Merve Gurakar
Murat Harputluoglu
Gokhan Kabacam
Sedat Karademir
Murat Kiyici
Ramazan Idilman
Zeki Karasu
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The combination of hepatitis B immunoglobulin and potent nucleos(t)ide analogs after liver transplantation is considered as the standard of care for prophylaxis against hepatitis B virus recurrence. However, the recommended doses, route of administration, and duration
of HBIG administration remain unclear. Moreover, hepatitis B immunoglobulin-free prophylaxis with potent nucleos(t)ide analogs has
shown promising disease outcomes in preventing hepatitis B virus recurrence. The current recommendations, produced by the Turkish
Association for the Study of the Liver, Acute Liver Failure and Liver Transplantation Special Interest Group, suggest a reduced need for
hepatitis B immunoglobulin administration with effective long-term suppression of hepatitis B virus replication using potent nucleos(t)
ide analogs after liver transplantation.
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