Recommendations for hepatitis B immunoglobulin and antiviral prophylaxis against hepatitis B recurrence after liver transplantation
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info:eu-repo/semantics/openAccessTarih
2021Yazar
Akarsu, MesutÖnem, Soner
Turan, İlker
Adalı, Gupse
Akdoğan, Meral
Akyıldız, Murat
Aladağ, Murat
Balaban, Yasemin
Danış, Nilay
Dayangaç, Murat
Gençdal, Genco
Gökcan, Hale
Sertesen, Elif
Gürakar, Merve
Harputluoğlu, Murat
Kabaçam, Gökhan
Karademir, Sedat
Kıyıcı, Murat
İdilman, Ramazan
Karasu, Zeki
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Akarsu, M., Onem, S., Turan, I., Adali, G., Akdogan, M., Akyildiz, M., ... & Karasu, Z. (2021). Recommendations for Hepatitis B Immunoglobulin and Antiviral Prophylaxis Against Hepatitis B Recurrence After Liver Transplantation. The Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology, 32(9), 712-719.Özet
he combination of hepatitis B immunoglobulin and potent nucleos(t)ide analogs after liver transplantation is considered as the standard of care for prophylaxis against hepatitis B virus recurrence. However, the recommended doses, route of administration, and duration of HBIG administration remain unclear. Moreover, hepatitis B immunoglobulin-free prophylaxis with potent nucleos(t)ide analogs has shown promising disease outcomes in preventing hepatitis B virus recurrence. The current recommendations, produced by the Turkish Association for the Study of the Liver, Acute Liver Failure and Liver Transplantation Special Interest Group, suggest a reduced need for hepatitis B immunoglobulin administration with effective long-term suppression of hepatitis B virus replication using potent nucleos(t) ide analogs after liver transplantation.
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