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    Can complete blood counts and ratios be an adjunct to prostate specific antigen for avoiding unnecessary transrectal ultrasound-guided prostate biopsy?
    (Logos Medical Publishing, 2016) Amasyali, Akin Soner; Koç, Akif; Yıldırım, Mehmet Erol; Sarı, Erhan; Güler, Cem; Erol, Haluk
    We aimed to evaluate, if complete blood counts (CBC) evaluated before prostate biopsy could predict the result of the prostate biopsy performed due to the increased PSA levels. We retrospectively reviewed the data of 281 patients who had undergone prostate biopsy because of the increased levels of PSA in three university hospital. Patient’s age, pre-biopsy CBC, total PSA, free PSA, prostate volume and biopsy results were recorded. Patients were grouped according to the prostate biopsy results as; I: prostate cancer, II: Benign prostate hiperplasia, III: chronic prostatitis. We invastigated whether CBC counts and their ratios of this counts have any statistically significant predictive value in the three groups. A statistically significant difference was detected among the three groups regarding platelet count, neutrophil/monocyte (NMR) and platelet/lymphocyte ratios (PLR). The patelet count and PLRs were significantly higher in Group III rather than Groups I and II. Also the NMR was significantly higher in Group III than Group II. We have shown that pre-biopsy platelet count, NMR and PLR could predict thethe outcome of chronic prostatitis who had undergone prostate biopsy because of the increased levels of PSA. Furthermore, prospective case-controlled, large studies would be helpful to explore the predictive value of CBC on the prostate biopsy results. © 2021 Elsevier B.V., All rights reserved.