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    Clinical reflection of anatomical evaluation in coccydynia
    (Soc Anatomica Espanola, 2024) Guler, Emel; Guler, Ilkay; Arslan, Ayla; Uzun, Gokce Bagci
    Coccydynia is a pain in the coccyx and the surrounding anatomical structures. Our aim in the study was to evaluate whether the disease duration, pain assessment, and coccyx morphological type had an effect on this clinic in patients with a diagnosis of coccydynia. A total of 68 coccyx Magnetic Resonance Imaging (MRI) results were evaluated. Coccyx segment number, morphological typing, lumbosacral, sacrococcygeal, and intercoccygeal angle measurements were made. Disease duration, day and night movement and the rest of Numerical Pain Scale (NRS) values were recorded from existing records of patients with a diagnosis of coccydynia. When the morphological typing was evaluated, type 4 subluxation was found to be high in the group with coccydynia. Pain complaint duration was 13.94 +/- 12.22 months, sitting time was 16.82 +/- 14.22 minutes, and the numerical pain scale was 7.62 +/- 1.48. Morphologically, type 1;14 (3 coccydynia), type 2;22 (9 coccydynia), type 3;14 (6 coccydynia), type 4;18 (16 coccydynia) images were also detected. A moderately statistically significant positive cor-- relation was found between the sacrococcygeal and intercoccygeal angles (p<0.05). We believe that evaluating clinical data and anatomical measurements together will contribute to the treatment of coccydynia, which is especially difficult to treat.
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    Effect of carnosine on ovarian follicle in rats exposed to electromagnetic field
    (Soc Anatomica Espanola, 2022) Arslan, Ayla; Balcioglu, Esra; Nisari, Mehtap; Yalcin, Betul; Ulger, Menekse; Guler, Emel; Uzun, Gokce Bagci
    The electromagnetic field (EMF) has an effect on various organs, including the female reproductive system. The purpose of this study was to evaluate the impact of carnosine on ovarian follicle number and diameter in rats exposed to a 900 Megahertz (Mhz) electromagnetic field. In this study, six different groups were used. 40 female rats divided into groups were evaluated. The ovaries of the rats were removed at the end of the study. Routine histological procedures were performed on ovarian tissues. Follicle number and diameter of all groups were calculated and evaluated under the light microscope. When primary follicle number and diameters were compared statistically among the groups, there was a remarkably meaningful difference between the EMF group and the control, 20 mg carnosine and EMF+20 mg carnosine groups (p<0.05). There were significant irregularities in the structure of the oocyte and the granulosa cells surrounding the oocyte, especially in the EMF-treated groups. However, the structure of the oocyte and the granulosa cells surrounding the oocyte in the EMF+20 mg carnosine group showed a more regular structure compared to the EMF group. In this study, it can be concluded that the number and diameter of ovarian follicles decreased in rats exposed to electromagnetic field and 20 mg of carnosine may prevent damage caused by EMF.
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    Investigating the anti-tumoral effect of yarrow (Achillea milllefolium) on the mice in which ehrlich solid tumor is created
    (Humana Press Inc, 2022) Uzun, Gokce Bagci; Nisari, Mehtap; Yay, Arzu Hanim; Karatoprak, Gokce Seker; Al, Ozge; Ucar, Sumeyye; Arslan, Ayla
    In this study, BALB/c mice with Ehrlich solid tumors were used to examine the effect of Achillea millefolium L. (AM) extract on the Ehrlich ascites tumor (EAT) model, which is one of the experimental cancer models. Also known as yarrow and plant, AM has antioxidant, anti-inflammatory, antibacterial and antitumor properties. In our study, 57 male BALB/c type mice, 8-10 weeks old, weighing 25-30 g, were used. Mice were divided into two groups. Ehrlich Solid Tumor group: Negative Control Group (ENC), Positive Control Group (EPC), and Treatment Group (TG) (TNCAM-200 mg/kg, TPCAM-400 mg/kg). EPC and TG were given to EAT cells. Each EAT contained 1 x 106 (will be 6 out of 10: so:000000) EAT cells, 0.1 ml of phosphate-buffered saline (PBS) was administered subcutaneously (s.c.) to the nape of mice. Then It was awaited for solid tumor formation. AM extract was administered intraperitoneally (i.p.) to TG for 17 days to mice. AM extract was found to have a curative effect on areas of inflammation, bleeding, and necrosis in treatment groups treated with AM extract alone. The treatment groups showed nearly normal histological results compared to the positive control group. According to the results, the TPCAM-400 mg/kg group had a more significant histological impact than the TNCAM-200 mg/kg group. In terms of tumor growth, tumor length, tumor volume, and tumor weight, AM extract did not show significant effects. However, in the light of histological findings, promising results of AM were observed in mice in which Ehrlich Solid Tumor was formed.
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    Relationship between post traumatic stress disorder and hand dimensions and hand grip strength in children aged 8-12 exposed to earthquakes
    (Nature Portfolio, 2024) Uzun, Gokce Bagci; Arslan, Ayla; Arpaci, Muhammed Furkan; Demirel, Emre; Karakas, Nese
    Earthquakes cause severe destruction in the region where they occur. Children and adolescents are the group most affected group by earthquakes, and Post-Traumatic Stress Disorder is most common in this group. The age-related increase in Grip Strength varies between childhood and early adolescence. The purpose of the present study was to investigate the relationship between Post Traumatic Stress Disorder and Hand Grip and Hand Measurements of children exposed to the Kahramanmara & scedil;-centered earthquake on February 6, 2023. The Post-Traumatic Stress Disorder Response Scale for Children was administered to 116 children who in children between the ages of 8 and 12 groups, and consent was obtained from the participants. Morphometric measurements of the hands of the children were measured with a digital caliper. Children's hand Grip Strength measurements were made by using a digital hand dynamometer. The analysis of study data was performed with the SPSS (Statistical Program in Social Sciences) 25 software. Positive and statistically significant relationships were detected between right and left-hand Grip Strength and right and left-hand measurements of females and males (p < 0.05). Statistically significant and negative relationships were detected between PTSD and right and left-hand Grip Strength and right and left-hand measurements in females and males (p < 0.05).In the present study, it was detected that as post-traumatic stress disorder increases, hand Grip Strength decreases. We think that these findings will guide future prospective studies.