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    Impact of black carrot juice on acrylamide-induced structural alterations in rats' testicles
    (2025) PEKMEZ, HIDIR; ESEN, Gülru; yalçın, alper; TÜRK, AHMET; CETIN, Seda; Yanılmaz, Elif; KAYA, Anıl
    Aim: The purpose of this study was to investigate the deleterious effects of acrylamide on rat testicular tissue and to determine how these effects might vary in response to black carrot juice. Materials and Methods: Four groups of adult male Wistar albino rats were formed: Control, Acrylamide, Black carrot juice and Acrylamide + Black carrot juice. For 30 days, 20 mg/kg acrylamide dose was administered intraperitoneally and 4 mg/kg black carrot juice dose was administered orally every second day. Results: Malondialdehyde and glutathione S-transferase levels rose in the acrylamide group relative to the control group, whereas the levels of the enzymes glutathione and carboxylesterase dropped. Malondialdehyde and glutathione S-transferase levels were lower in the acrylamide+black carrot juice group than in the acrylamide group, whereas glutathione and carboxylesterase enzyme activity levels were higher. Conclusion: Lipid peroxidation was discovered as a result of acrylamide’s detrimental effects on the antioxidant enzyme system. It was observed that black carrot juice had positive effects.