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    Relationship between oxidant and antioxidant activity in hyperemesis gravidarum
    (Taylor & Francis Ltd, 2014) Onaran, Yuksel; Kafali, Hasan; Duvan, Candan Iltemir; Keskin, Esra; Celik, Hakim; Erel, Ozcan
    Objective: To evaluate oxidant and antioxidant activity in patients with hyperemesis gravidarum (HG) by using serum total antioxidant activity (TAO), total free sulfhydryl (-SH), ceruloplasmin and lipid hydroperoxide (LOOH) levels. Materials and methods: In a cross-sectional trial, blood samples were collected from patients with HG (n = 25) and healthy pregnant women (n = 25) as control group. Serum TAO activities, -SH levels and LOOH levels and ceruloplasmin levels were measured. Results: Serum TAO activity was found to be significantly lower (p = 0.003) in patients with HG compared with controls. However, serum -SH levels, LOOH levels and ceruloplasmin levels did not change significantly in patients with HG compared to controls. Conclusion: Presence of oxidative stress in HG patients depends more on reduced antioxidant activities than increased oxidative stress.