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    Adolescent pregnancy and depression: is there an association?
    (7847050 Canada Inc, 2016) Kamalak, Z.; Kosus, N.; Kosus, A.; Hizli, D.; Akcal, B.; Kafali, H.; Canbal, M.
    Objective: The impact of being an adolescent and socio-demographic parameters on depression development during pregnancy were evaluated in this study. Materials and Methods: Between September 2010 and September 2011, 105 consecutive adolescent women <= 17 years of age were defined as the study group and 105 consecutive pregnant women over 18 years of age and matched for gestational age, were defined as the control group. Groups were compared according to depression development. The predictors of depression were analyzed by regression analysis. Results: Median Beck Depression Inventory-II (BDI-II) scores in adolescent and control groups were 16 and 6, respectively. The difference was statistically significant. In the adolescent group, 39.0% of patients had mild depression, 37.1% moderate, and 10.5% had severe depression. Only 4.8% of patients in the control group had mild depression while none of the control cases had moderate or severe depression. Multivariate analysis showed that most important factor that was associated with depression development during pregnancy was being an adolescent. Conclusion: Depression risk was increased 18.2-fold in adolescent patients with pregnancy. Therefore psychiatric evaluation should be considered for these patients.
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    Bupivacaine-soaked absorbable gelatin sponges in caesarean section wounds: effect on postoperative pain, analgesic requirement and haemodynamic profile
    (Elsevier Sci Ltd, 2014) Simavli, S.; Kaygusuz, I.; Kinay, T.; Baylan, A. Akinci; Kafali, H.
    Background: Pain is a common distressing adverse effect in the early postoperative period following caesarean section. The aim of this study was to investigate the effect on postoperative pain, analgesic requirement and haemodynamic profile of placing a suprafacial bupivacaine-soaked absorbable gelatin sponge in the caesarean section wound. Methods: A total of 164 healthy patients scheduled to undergo general anaesthesia for elective caesarean section were randomised to a study group (n=81) or a control group (n=83). In the study group, a bupivacaine-soaked absorbable gelatin sponge was placed subcutaneously in the caesarean section wound. Intramuscular diclofenac 75 mg was given to all patients at 8-h intervals during the first 24 h. Postoperatively, visual analogue scale pain scores, requirement for pethidine and diclofenac and changes in blood pressure and heart rate were compared between groups. Results: Pain scores were lower in the study group compared to the control group at all assessments (P <0.001). During the first eight hours after surgery, fewer patients in the study group required rescue pethidine compared with the control group (4 vs. 33, P <0.001). In the study group, total opioid and diclofenac consumption was lower (P <0.001), and blood pressure and heart rate were lower (P <0.001) compared to the control group. Conclusion: Suprafascial wound placement of a bupivacaine-soaked absorbable gelatin sponge improved postoperative analgesia and decreased opioid consumption following caesarean section. (C) 2014 Elsevier Ltd. All rights reserved.
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    DOES ETONOGESTREL CONTRACEPTIVE IMPLANT (IMPLANON) EFFECT BONE METABOLISM DURING LACTATION PERIOD?
    (Elsevier Science Inc, 2013) Duvan, C. Iltemir; Onaran, Y.; Keskin, E. Aktepe; Yanik, B.; Kafali, H.; Turhan, N. Ozturk
    [Abstract Not Available]
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    DOES IGNORING OF THE THE GnRH-ANTAGONISTS ON THE DAY OF hCG EFFECT CYCLE OUTCOME DURING GnRH-ANTAGONIST PROTOCOL?
    (Elsevier Science Inc, 2013) Duvan, C. Iltemir; Onaran, Y.; Ayrim, A.; Pekel, A.; Kafali, H.; Turhan, N. Ozturk
    [Abstract Not Available]
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    Does quality of female sexual function improve after a transobturator tape procedure?
    (Taylor & Francis Inc, 2014) Kamalak, Z.; Kosus, A.; Hizli, F.; Kosus, N.; Hizli, D.; Kafali, H.
    The aim of this study was to use a questionnaire to evaluate any changes in sexual satisfaction of women who underwent a transobturator tape (TOT) procedure for stress urinary incontinence. A total of 30 women agreed to participate in the study and were invited to fill out the Female Sexual Function Index (FSFI) questionnaire prior to surgery and 3 months after surgery. As a result, after the TOT operation, there was a statistically significant improvement in libido (desire), arousal, lubrication, orgasm and satisfaction. The TOT procedure seems to have a positive effect on female sexual function by reducing the urinary leakage during sexual activity and by decreasing the pain during or after sexual activity.
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    EVALUATION OF SERUM AND FOLLICULAR FLUID LEVELS OF SOLUBLE FAS, SOLUBLE FAS LIGAND AND OXIDATIVE STRESS PARAMETERS OF PATIENTS UNDERGOING IVF
    (Elsevier Science Inc, 2013) Pekel, A.; Gonenc, A.; Turhan, N. Ozturk; Kafali, H.; Gurcan, S.
    [Abstract Not Available]
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    Protective effect of curcumin on ovarian reserve in a rat ischemia model: an experimental study
    (I R O G Canada, Inc, 2017) Eser, A.; Hizli, D.; Namuslu, M.; Haltas, H.; Kosus, N.; Kosus, A.; Kafali, H.
    Purpose of investigation: To determine the protective effect of curcumin on ovarian reserve in a rat ischemia model. Materials and Methods: Thirty female Albino rats were randomly divided into two groups by time of unilateral, left ovary ischemia/reperfusion (group 1: two-hour ischemia / two-hour reperfusion; group 2: four-hour ischemia / four-hour reperfusion). Each group was subdivided into three subgroups, sham, control, and curcumin (intraperitoneal curcumin (200 mg/kg) simultaneously with reperfusion). Histological grading of ischemic indices of paraffin-embedded ovarian tissue using hematoxylin and eosin (H&E), and anti-Mullerian hormone (AMH) levels by enzyme-linked immunosorbent assay (ELISA), were measured 40 days later. Results: No difference was found between groups 1 and 2 or among subgroups within either group for right and left ovary grades. AMH levels were significantly higher in the curcumin subgroup compared to sham and control within group 2 and in group 2 versus group 1 curcumin subgroups. Conclusion: Curcumin maintains and protects ovarian functions in an ischemia-reperfusion rat model.