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    A POSSIBLE RELATIONSHIP BETWEEN RESPIRATORY MUSCLE WEAKNESS AND FAMILIAL MEDITERRANEAN FEVER: A CASE REPORT
    (Turkey Assoc Physiotherapists, 2014) Cirak, Yasemin; Yilmaz, Gul Deniz; Demir, Yasemin P.; Karahan, Zehra; Dalkilinc, Murat
    To Familial Mediterranean Fever (FMF) is an autoinflammatory disorder with genetic origin. Pleuritis is most common in FMF. Long-term sequelae of respiratory system haven't been described in FMF. We documented pulmonary manifestations in patient with FMF. A 61-year-old woman presented with dyspnea, unilateral chest pain, generalized myalgia and FMF. Physical examination was unremarkable. Radiological data showed left-sided pleuritis, minimal pleural effusion. Pleural effusion resolved spontaneously in one week later but patient had still dyspnea. Pulmonary function tests (PFT) was normal. Further examination detected respiratory muscle weakness and decreased functional capacity. Patient then underwent inspiratory muscle training (IMT) for six weeks. After training, inspiratory muscle strength and functional capacity increased. Perception of dyspnea and fatique decreased. In long-term follow-up, frequency of attacks decreased. To our knowledge, there is no study on respiratory muscle weakness and IMT in FMF. Although this report doesn't provide direct evidence, it may provide recommendation for investigation of respiratory muscle weakness and treatment with IMT in FMF with respiratory impairments. Randomized controlled trials are needed.
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    Quality of life following acute deep vein thrombosis: the cultural adaptation, reliability and validity of the VEINES-QOL/Sym scale: a Turkish version study
    (Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2013) Cirak, Yasemin; Savci, Sema; Karahan, Zehra; Demirkilic, Ufuk
    Background: This study aims to translate and make cultural adaptation of a widely used Venous Insufficiency Epidemiologic and Economic Study Quality-of-Life Questionnaire (VEINES-QOL/Sym) into Turkish according to international guidelines and to statistically evaluate its validity and reliability by administering it to Turkish-speaking patients with acute deep vein thrombosis (DVT). Methods: Translation and cultural adaptation of the questionnaire were performed. It was administered to 31 patients with acute DVT. The VEINES-QOL/Sym was performed 5-7 days after its initial application to evaluate its test-retest reliability. The internal consistency was assessed through Cronbach's alpha (including if item was deleted), test-retest reliability was assessed through the intraclass correlation coefficient. Validity was examined by correlation of VEINES-QOL/Sym with Nottingham Health Profile (NHP) and the distance of six-minute walk test (6MWT). Results: Cronbach's alfa values were 0.96 for the VEINES-QOL and 0.94 for the VEINES-Sym. No problematic items were observed for the scale. Intraclass correlation coefficient score for test-retest reliability were 0.984 and 0.996 for VEINES-QOL and VEINES-Sym scores, respectively. The VEINES-QOL/Sym scale was considered highly reliable. When the relation between VEINES-QOL/Sym and the distance of 6MWT was investigated, the relation of VEINES-QOL was moderate (r=0.372; p<0.05), and of VEINES-Sym was excellent (r=0.890; p<0.01). When the relation between VEINES-QOL/Sym and NHP was investigated, the r value was -0.359 (moderate; p<0.05) for VEINES-Sym and -0.393 (moderate; p<0.05) for VEINES-QOL. Conclusion: The Turkish VEINSES-QOL/Sym is a reliable, valid and easy to understand tool for the measurement of the quality of life and symptoms in Turkish-speaking patients with DVT.