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  • Küçük Resim Yok
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    Palynological, chemical, antimicrobial, and enzyme inhibition properties of Cannabis sativa L. propolis
    (Springer, 2023) Ozkok, Asli; Karlidag, Semiramis; Keskin, Merve; Bayram, Sinan; Keskin, Saban; Karabulut, Ercan; Yilmaz, Ismet
    In this study, both chemical characterization and biological activities of propolis samples obtained from Cannabis sativa L. (cannabis, hemp, marijuana) isolated colonies (research group) and obtained from colonies at a distance where the bee cannot fly to the isolation area (control group) were determined. Palynological analyses of propolis samples obtained from the research and control group colonies were made and the botanical origin of the cannabis plant and other plants in the research area and the plants in the control group were determined. Bioactive component analysis of propolis extracts was determined by the GC-MS technique. The inhibition effect of propolis samples on some enzymes of medical importance and their antimicrobial effects against many pathogenic microorganisms were also investigated. Palynological analyses showed that honey bees prefer cannabis plants (11.11%) when collecting propolis, and the dry matter percentage (94.6 +/- 1.8%), balsam (46.2 +/- 5.2%), and wax content (4.8 +/- 0.5%), total phenolic (26.44 +/- 1.08 mg GAE/mL) and total flavonoid (2.03 +/- 0.11 mg QE/mL) content and antioxidant capacity (88.16 +/- 2.27 mu M FeSO4 center dot 7H(2)O/mL(-1)) of the research group propolis samples containing hemp were found to be higher than the control group. Also, it was determined that the research group propolis sample contains cannabinoid derivatives (cannabidivarinic acid, 0.29%; delta (1)-tetrahydrocannabinolic acid, 0.59%; cannabidiolic acid, 0.48%), which are active compounds of the cannabis plant. Also, a high inhibition effect was detected on some enzymes of medical importance in propolis samples obtained from cannabis group colonies. In addition, the research group propolis samples also showed a high antimicrobial effect against many pathogenic microorganisms.
  • Küçük Resim Yok
    Öğe
    Treatment of injuries in javelin horses with propolis
    (Univ Zulia, Facultad Ciencias Veterinarias, 2025) Gokhan, Nezihe; Keskin, Merve; Karlidag, Semiramis; Keskin, Saban; Sarici, Oguzcan; Ozyildiz, Zafer
    Debridement and suturing of deep and infected wounds in horses requires sedation and anesthesia due to the limitations of horses. For this reason, it is preferred to perform wound treatment and care with more practical methods. The aim of this study is to evaluate wound healing in 18 horses by utilizing the antimicrobial, anti- inflammatory and local anesthetic effects of propolis. Various wounds resulting from trauma on 18 male, Arabian and British horses aged between 3-8 at Malatya Equestrian Javelin Club were treated by applying liquid propolis in spray form for 5 days. Wound size was measured with a ruler on days 1, 3, 5, 9, 13, 15 and 21 provides healing in a short time.