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    Can complete blood counts and ratios be an adjunct to prostate specific antigen for avoiding unnecessary transrectal ultrasound-guided prostate biopsy?
    (Logos Medical Publishing, 2016) Amasyali, Akin Soner; Koç, Akif; Yıldırım, Mehmet Erol; Sarı, Erhan; Güler, Cem; Erol, Haluk
    We aimed to evaluate, if complete blood counts (CBC) evaluated before prostate biopsy could predict the result of the prostate biopsy performed due to the increased PSA levels. We retrospectively reviewed the data of 281 patients who had undergone prostate biopsy because of the increased levels of PSA in three university hospital. Patient’s age, pre-biopsy CBC, total PSA, free PSA, prostate volume and biopsy results were recorded. Patients were grouped according to the prostate biopsy results as; I: prostate cancer, II: Benign prostate hiperplasia, III: chronic prostatitis. We invastigated whether CBC counts and their ratios of this counts have any statistically significant predictive value in the three groups. A statistically significant difference was detected among the three groups regarding platelet count, neutrophil/monocyte (NMR) and platelet/lymphocyte ratios (PLR). The patelet count and PLRs were significantly higher in Group III rather than Groups I and II. Also the NMR was significantly higher in Group III than Group II. We have shown that pre-biopsy platelet count, NMR and PLR could predict thethe outcome of chronic prostatitis who had undergone prostate biopsy because of the increased levels of PSA. Furthermore, prospective case-controlled, large studies would be helpful to explore the predictive value of CBC on the prostate biopsy results. © 2021 Elsevier B.V., All rights reserved.
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    The association between serum follicle-stimulating hormone levels and the success of microdissection testicular sperm extraction in patients with azoospermia
    (Urology and Nephrology Research Centre info@unrc.ir, 2014) Yıldırım, Mehmet Erol; Koç, Akif; Kaygusuz, İkbal Cekmen; Badem, Hüseyin; Karataş, Ömer Faruk; Çimentepe, Ersin In; Ünal, Doğan
    Purpose: To evaluate the predictive power of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, testicular biopsy histology and male age were evaluated with respect to the success of sperm retrieval in a microdissection testicular sperm extraction (microTESE) procedure, pregnancy and live birth rates. Materials and Methods: We examined the data of 131 infertile men with non-obstructive azoospermia, who have undergone microTESE operation. The men were classified into two groups based on serum follicle-stimulating hormone (FSH) levels ? 15 mIU/mL (group 1) and > 15 mIU/mL (group 2). Results: Group 1 consisted of 59 patients (mean age 36.2 ± 6.2 years) and group 2 consisted of 72 (mean age 38.8 ± 7.4 years) patients. Sperm retrieval and pregnancy rates were 66.1% and 16.9% in normal FSH group, respectively. These parameters were higher than those of men with FSH > 15 (43% and 8.3%, respectively). Only 128 patients had histopathological diagnosis. Sperm was retrieved from 12/30 (40%) patients with maturation arrest, 9/29 (31.03%) patients with seminiferous tubules atrophy, 14/40 (35%) patients with sertoli cell only syndrome and 13/13 (100%) of patients with hypospermatogenesis. There was no statistically significant difference in pathological diagnosis between pregnancy and live birth rates. Conclusion: These results demonstrate that there is a significant difference with sperm retrieval, pregnancy rates and live birth rates comparing the FSH levels. Histopathological findings did not associate with successful microTESE, pregnancy rates and live birth rates. © 2015 Elsevier B.V., All rights reserved.