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    Morbidity and mortality results of COVID-19 variant in COVID-19 positive patients treated in the intensive care unit
    (Bayrakol Medical Publisher, 2023) Aydin, Ahmet; Koca, Erdinc; Kutlusoy, Sevgi; Kasapoglu, Umut Sabri
    Aim: COVID-19 has the potential to affect many systems and organs, resulting in serious clinical symptoms that necessitate admission to the intensive care unit. The purpose of this study was to examine the relationship between CAR, other laboratory findings, comorbidities, and mortality in patients infected with the original SARSCoV-2 or other variants.Materials and Methods: The data of 368 patients admitted to the intensive care unit with COVID-19 pneumonia between March 2020 and July 2021 were analyzed. These patients were divided into two groups. The first group included [(OC) Original SARSCoV-2 ] COVID-19 infected patients in the first period of the pandemic. The second group [(OV) Other Variants] included patients with COVID-19 infection due to other variants.Results: The mean age (Mean +/- SD) in the OC group was 69.79 +/- 11.77 years. The mean age of the patients in OC was higher than in the OV group (p=0.001). The most common comorbid disease in both groups was Hypertension (54.1%, 48.8%), followed by diabetes mellitus (DM) (30.2%, 31.6%). The mean age of the survivors in the OC and OV groups was lower (64.53 +/- 13.04, 57.85 +/- 16.78, p=0.001, p=0.001, respectively). It was observed that albumin and lymphocyte counts were lower in the deceased, while LDH, CRP, Neutrophil, procalcitonin, NLR and CAR were higher (p<0.05). Discussion: In critically ill COVID-19 patients, high CAR and NLR are good predictors of mortality. In the period when the variants were dominant, the mean age of the patients and the length of stay in the intensive care unit were lower.
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    Our tracheostomy results in the intensive care unit, outcomes of 199 patients
    (Bayrakol Medical Publisher, 2022) Koca, Erdinc; Koca, Cigdem Firat
    Aim: The history of tracheostomy goes back to 3600 BC. Percutaneous dilatational tracheostomy was described in 1985 by Ciaglia. Percutaneous dilatational tracheostomy is quick, less traumatic, and has fewer complications. The aim of our study was to analyze the tracheostomy results of 199 patients in our Intensive Care Units. Material and Methods: We included patients who underwent tracheostomy in our Intensive Care Units between January 2014 and December 2018 in Malatya Training and Research Hospital. A retrospective analysis was carried out for diagnosis, complications, surgical tracheostomy requirement reasons, demographics, comorbidity, ICU stay period, date of tracheostomy procedure, days to tracheostomy procedure from day of admission to ICU, days to tracheostomy procedure from initial tracheal intubation, days connected to mechanical ventilation, tracheostomy technique, urgent or elective, the final state of the patients were analyzed. Data were collected from the patients' records. The data of the study was evaluated through SPSS 'statistical package for social sciences' (spss17.0) 'program. Results: The average age of discharged patients was 56.3 years and 74.4 for the dead patient group. There was a statistically significant increase between age and mortality, and between Apache II score and mortality (p<0.05). Discussion: According to our study results, percutaneous tracheostomy is a method with a low complication rate and easy applicability. No statistically significant results were found between the time from admission to the intensive care unit to the day of tracheostomy opening, the time to stay intubated, and mortality.
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    PROGNOSIS OF GERIATRIC COVID-19 PATIENTS ADMITTED TO INTENSIVE CARE UNIT ACCORDING TO VACCINATION STATUS
    (Turkish Geriatrics Soc, 2022) Aydin, Ahmet; Kacmaz, Osman; Koca, Erdinc; Kutlusoy, Sevgi; Kasapoglu, Umut Sabri; Oterkus, Mesut
    Introduction: As of June 27, 2022, the COVID-19 pandemic has caused over 540 million infections and 6.3 million deaths. We aimed to investigate the effect of the vaccine on the clinical course of elderly patients hospitalized in the intensive care unit and to determine the prognosis of the patients according to their vaccination status. Materials and Methods: The study included 157 patients over the age of 65. Patients were divided into two groups. The first group consisted of patients who were vaccinated with two doses of CoronaVac, and the second group consisted of patients who were not vaccinated. Demographic data of the patients, prehospital clinical frailty scales, Charlson Comorbidity Indexes, APACHE II scores, laboratory values, and patient prognoses were recorded. Results: Of the 157 patients, 93 (59.2%) were female, and the median age was 76 years (65-99). 96 (61.1%) patients were vaccinated and 61 (38.9%) patients were unvaccinated. Patients were grouped as survivors (n=26) and deceased. We found that APACHE II, prehospital clinical frailty scales, and Charlson Comorbidity Indexes scores were higher in patients who died. There was a significant difference between blood lymphocyte and ferritin levels and survival. The 28-day survival rate was higher and intensive care unit overall survival time were longer in the vaccinated group. Conclusions: We observed that the vaccinated patients had higher survival times and lower mortality rates than those who were not vaccinated. We think that it is important to vaccinate elderly patients and that additional doses may be needed.
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    The effect of coronary artery bypass grafting procedure on audiovestibular system
    (Bayrakol Medical Publisher, 2023) Koca, Cigdem Firat; Koca, Erdinc
    Aim: Coronary artery bypass grafting surgery may affect end-organ perfusion. Our aim was to examine the effect of this method on audiovestibular system.Material and Methods: Patients who had CABG were called and invited. Pure tone audiometric test, c-and o-VEMP tests were performed for all participants.Results: The results at 250, 500, 2000 and 4000 Hz differed for the left ears (p=0,013, p=0,045, p=0,028, p=0,045 ) and in the right ears, p13 (p = 0.040) were differentiated among the groups and the p13-n23 amplitude was lower in the bypass group (p=0,013). In the left ear results , p13-n23 amplitude (p= 0.007) and n10-p15 amplitudes (p = 0.006) differed between the groups, and the right ear n10-p15 amplitudes were lower in the bypass group (p = 0,005). Mean n10 (p=0,006) and p15 latency were high in the bypass patients (p= 0,005).Discussion: CBAG may affect balance-connected mechanisms at varied levels and intensity.