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    A Hybrid Model with Quantum Feature Map Based on CNN and Vision Transformer for Clinical Support in Diagnosis of Acute Appendicitis
    (Mdpi, 2026) Ogut, Zeki; Karaduman, Mucahit; Bozdag, Pinar Gundogan; Karakose, Mehmet; Yildirim, Muhammed
    Background/Objectives: Rapid and accurate diagnosis of acute appendicitis is crucial for patient health and management, and the diagnostic process can be prolonged due to varying clinical symptoms and limitations of diagnostic tools. This study aims to shorten the timeframe for these vital processes and increase accuracy by developing a quantum-inspired hybrid model to identify appendicitis types. Methods: The developed model initially selects the two most performing architectures using four convolutional neural networks (CNNs) and two Transformers (ViTs). Feature extraction is then performed from these architectures. Phase-based trigonometric embedding, low-order interactions, and norm-preserving principles are used to generate a Quantum Feature Map (QFM) from these extracted features. The generated feature map is then passed to the Multiple Head Attention (MHA) layer after undergoing Hadamard fusion. At the end of this stage, classification is performed using a multilayer perceptron (MLP) with a ReLU activation function, which allows for the identification of acute appendicitis types. The developed quantum-inspired hybrid model is also compared with six different CNN and ViT architectures recognized in the literature. Results: The proposed quantum-inspired hybrid model outperformed the other models used in the study for acute appendicitis detection. The accuracy achieved in the proposed model was 97.96%. Conclusions: While the performance metrics obtained from the quantum-inspired model will form the basis of deep learning architectures for quantum technologies in the future, it is thought that if 6G technology is used in medical remote interventions, it will form the basis for real-time medical interventions by taking advantage of quantum speed.
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    Clinically Focused Computer-Aided Diagnosis for Breast Cancer Using SE and CBAM with Multi-Head Attention
    (Mdpi, 2025) Ogut, Zeki; Karaduman, Mucahit; Yildirim, Muhammed
    Background/Objectives: Breast cancer is one of the most common malignancies in women worldwide. Early diagnosis and accurate classification in breast cancer detection are among the most critical factors determining treatment success and patient survival. In this study, a deep learning-based model was developed that can classify benign, malignant, and normal breast tissues from ultrasound images with high accuracy and achieve better results than the methods commonly used in the literature. Methods: The proposed model was trained on a dataset of breast ultrasound images, and its classification performance was evaluated. The model is designed to effectively learn both local textural features and global contextual relationships by combining Squeeze-and-Excitation (SE) blocks, which emphasize channel-level feature importance, and Convolutional Block Attention Module (CBAM) attention mechanisms, which focus on spatial information, with the MHA structure. The model's performance is compared with three commonly used convolutional neural networks (CNNs) and three Vision Transformer (ViT) architectures. Results: The developed model achieved an accuracy rate of 96.03% in experimental analyses, outperforming both the six compared models and similar studies in the literature. Additionally, the proposed model was tested on a second dataset consisting of histopathological images and achieved an average accuracy of 99.55%. The results demonstrate that the model can effectively learn meaningful spatial and contextual information from ultrasound data and distinguish different tissue types with high accuracy. Conclusions: This study demonstrates the potential of deep learning-based approaches in breast ultrasound-based computer-aided diagnostic systems, providing a reliable, fast, and accurate decision support tool for early diagnosis. The results obtained with the proposed model suggest that it can significantly contribute to patient management by improving diagnostic accuracy in clinical applications.