Yazar "Seçkin, Turgay" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim
    Öğe
    Determination of characterization, antibacterial and drug release properties of POSSbased film synthesized with sol-gel technique
    (TÜBİTAK, 2021) Karaca Açarı, İdil; Köytepe, Süleyman; Ateş, Burhan; Yılmaz, İsmet; Seçkin, Turgay
    In the study, antibacterial film synthesis was aimed using sol-gel technique from POSS structure with various functional groups. For this purpose, antibacterial properties have been acquired by metronidazole to the films to be synthesized. The films obtained were coated on glass surface samples by dip coating method. Antibacterial activities of surface coated glass samples were observed in E.coli and S. aureus bacteria. Metronidazole release studies in the film samples were followed by UV spectrophotometer. It was observed that drug release reached 68.90% at the end of the 24th h. As a result, it is thought that the synthesized film will be a good candidate especially for biomedical surface coating areas.
  • Küçük Resim
    Öğe
    Synthesis and Characterization of Co-Doped SnO2 Samples
    (Bilecik Şeyh Edebali Üniversitesi, 2020) Ateş, Tankut; Kaygılı, Ömer; Bulut, Niyazi; Okur, Havva Esma; Keser, Serhat; Yahia, İ.S.; Köytepe, Süleyman; Seçkin, Turgay; Özcan, İmren; İnce, Turan
    The un-doped and Co-doped SnO2 samples having high crystallinity were successfully prepared. The effects of Co content on the structural, thermal and morphological properties of SnO2 were investigated. Changes in the crystallite size and unit cell parameters were detected with adding of Co. The phase composition did not alter with the addition of Co. Both X-ray diffraction and Fourier transform infrared results confirmed the formation of the SnO2 structure for each sample. The thermal stability of the as-produced samples from room temperature to 900 °C was observed. The morphology was affected by Co content, and energy dispersive X-ray results verified the introduction of Co into the SnO2 structure.
  • Küçük Resim
    Öğe
    Synthesis of polyhedral oligomeric silsesquioxane-n-acetylcysteine conjugate with click chemistry and ıts antioxidant response and biocompatibility
    (Cumhuriyet Üniversitesi, 2020) Karaca Açarı, İdil; Balcıoğlu, Sevgi; Ateş, Burhan; Köytepe, Süleyman; Yılmaz, İsmet; Seçkin, Turgay
    In this study, polyhedral oligomeric silsesquioxane-N-acetylcysteine (POSS-NAC) conjugate as a potential antioxidant molecule was synthesized from N-acetylcysteine (NAC) and aminofunctional POSS structure by click chemistry. The chemical structures and thermal properties of the synthesised POSS-NAC conjugate was characterized by spectroscopic and thermal analysis techniques. The antioxidant capacity of the POSS-NAC conjugate was also determined by the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity and reducing power methods. According to the reducing power method, POSS-NAC structure has lower reducing activity than standard ascorbic acid and trolox (p<0.001). It was found from the ABTS radical scavenging activity results that the synthesized POSS-NAC conjugate had a significantly higher radical scavenging effect than the standards (p <0.001). Biocompatibility properties of the POSS-NAC structure were detected in vitro cell culture system with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test on L-929 mouse fibroblast cells. The synthesized POSS-NAC conjugate exhibits high antioxidant activity and good biocompatibility