Evaluation of Aerobic Conjunctival Flora in Patients with Demodex Blepharitis

Basit Öğe Kaydı
dc.contributor.authorGündüz, Ayten
dc.contributor.authorDEMİREL, E ERSİN
dc.contributor.authorFırat, Murat
dc.date.accessioned2025-10-24T18:04:01Z
dc.date.available2025-10-24T18:04:01Z
dc.date.issued2022
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: Demodex species are frequently found in blepharitis cases. This study aimed to compare the conjunctival flora of eyes with Demodex-positive blepharitis and Demodex-negative blepharitis with healthy individuals. Methods: Eyelash epilation was performed to detect Demodex from 44 eyes of 44 patients with chronic blepharitis and 44 eyes of 44 healthy controls and examined under a microscope. A conjunctival swab was taken from the same eye and inoculated on eosin methylene blue agar, Sabouraud dextrose agar, chocolate agar, and 5% sheep blood agar. Aerobic conjunctival flora was evaluated among Demodex-positive blepharitis, Demodex-negative blepharitis and healthy eyes. Results: Demodex spp. was detected in 3 (6.8%) of 44 healthy controls and 24 (54.5%) of 44 patients with blepharitis. The most frequently isolated bacteria in healthy controls were coagulase-negative Staphylococci (CNS) spp. (n=32, 72.7%), Streptococcus spp. (n=16, 36.4%), Corynebacterium spp. (n=13, 29.5%). The most frequently isolated bacteria in Demodex-positive blepharitis were CNS spp. (n=14, 58.3%), Staphylococcus aureus (n=11, 45.8%), Corynebacterium spp. (n=7, 29.2%). In Demodex-negative blepharitis, CNS (n=10, 50.0%), S. aureus (n=10, 50.0%), Corynebacterium spp. (n=5, 25.0%) were most commonly isolated. S. aureus growth was significantly increased in the Demodex negative and positive blepharitis groups compared with the healthy group (p=0.001 and p=0.002, respectively). Although CNS spp. growth decreased in both groups with Demodex-negative and positive blepharitis compared with the healthy group; the decrease was significant only in those with Demodex-negative blepharitis (p=0.045). In terms of other bacterial growth, there was no significant difference between healthy eyes and Demodex positive and negative eyes with blepharitis. Conclusion: We found that Demodex blepharitis has no significant effect on conjunctival flora. Blepharitis itself may be the main factor in changes in the conjunctival flora.
dc.identifier.doi10.4274/tpd.galenos.2022.88942
dc.identifier.endpage306
dc.identifier.issn1300-6320
dc.identifier.issn2146-3077
dc.identifier.issue4
dc.identifier.startpage301
dc.identifier.trdizinid1173263
dc.identifier.urihttps://doi.org/10.4274/tpd.galenos.2022.88942
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1173263
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2601
dc.identifier.volume46
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTürkiye Parazitoloji Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzTR-Dizin_20251023
dc.subjectGöz Hastalıkları
dc.titleEvaluation of Aerobic Conjunctival Flora in Patients with Demodex Blepharitis
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu