Impact of black carrot juice on acrylamide-induced structural alterations in rats' testicles

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dc.contributor.authorPEKMEZ, HIDIR
dc.contributor.authorESEN, Gülru
dc.contributor.authoryalçın, alper
dc.contributor.authorTÜRK, AHMET
dc.contributor.authorCETIN, Seda
dc.contributor.authorYanılmaz, Elif
dc.contributor.authorKAYA, Anıl
dc.date.accessioned2025-10-24T18:03:46Z
dc.date.available2025-10-24T18:03:46Z
dc.date.issued2025
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractAim: The purpose of this study was to investigate the deleterious effects of acrylamide on rat testicular tissue and to determine how these effects might vary in response to black carrot juice. Materials and Methods: Four groups of adult male Wistar albino rats were formed: Control, Acrylamide, Black carrot juice and Acrylamide + Black carrot juice. For 30 days, 20 mg/kg acrylamide dose was administered intraperitoneally and 4 mg/kg black carrot juice dose was administered orally every second day. Results: Malondialdehyde and glutathione S-transferase levels rose in the acrylamide group relative to the control group, whereas the levels of the enzymes glutathione and carboxylesterase dropped. Malondialdehyde and glutathione S-transferase levels were lower in the acrylamide+black carrot juice group than in the acrylamide group, whereas glutathione and carboxylesterase enzyme activity levels were higher. Conclusion: Lipid peroxidation was discovered as a result of acrylamide’s detrimental effects on the antioxidant enzyme system. It was observed that black carrot juice had positive effects.
dc.identifier.doi10.30569/adiyamansaglik.1594967
dc.identifier.endpage9
dc.identifier.issn2458-9179
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.trdizinid1310918
dc.identifier.urihttps://doi.org/10.30569/adiyamansaglik.1594967
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1310918
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2438
dc.identifier.volume11
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofAdıyaman Üniversitesi Sağlık Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzTR-Dizin_20251023
dc.subjectTestis
dc.subjectOxidative stress
dc.subjectHistopathology
dc.subjectBlack carrot
dc.subjectAcrylamide
dc.titleImpact of black carrot juice on acrylamide-induced structural alterations in rats' testicles
dc.typeArticle

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