Relationship Between Viral Load and Laboratory Values and Radiological Findings in Patients with COVID-19

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dc.contributor.authorAltintop Geckil, Aysegul
dc.contributor.authorBenk, Isilay Gokce
dc.contributor.authorAydin, Sukru
dc.contributor.authorAkcicek, Mehmet
dc.date.accessioned2026-06-19T06:37:33Z
dc.date.available2026-06-19T06:37:33Z
dc.date.issued2022
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractIntroduction: This study investigates the relationship between the viral load calculated from oropharyngeal/nasopharyngeal swabs at diagnosis and the laboratory parameters and radiological findings in patients with Coronavirus disease-2019 (COVID-19). Materials and Methods: Sixty-seven patients who were positive for severe acute respiratory syndrome-coronavirus-2 via quantitative reverse transcription-polymerase chain reaction (qPCR) from their oropharyngeal/nasopharyngeal swabs and admitted to Malatya Turgut Ozal University Hospital were included in the study. Demographic data, laboratory parameters, and the severity of thorax computed tomography findings were recorded. The relationship between the viral load and these data was compared. Results: The mean age of the patients was 63.4 +/- 9.8 years, mean body mass index (BMI) was 28.6 +/- 5.4 kg/m(2), and mean cycle threshold (Ct) values were 21.4 +/- 5.2 cycles. No correlation was found between Ct value and gender, age, and BMI. There was a significant relationship between radiological severity and Ct value, age, and gender. There was a significant correlation between the Ct value and C-reactive protein, leukocyte, neutrophil, lymphocyte, neutrophil-lymphocyte ratio, ferritin, albumin, and calcium levels. In contrast, no significant correlation was found between hemoglobin, hematocrit, thrombocyte, urea, creatinine, total protein, gamma glutamyl transferase, alkaline phosphatase, sodium, potassium, D-dimer, procalcitonin levels, and Ct value. Conclusion: The viral load amount shown by PCR during the early period predicts the condition of the patient's lung in the advanced immunological phase. The Ct value can be an independent factor for evaluating the patient's radiological and biochemical status.
dc.identifier.doi10.4274/mjima.galenos.2022.2022.26
dc.identifier.issn2147-673X
dc.identifier.orcid0000-0003-1105-3338
dc.identifier.orcid0000-0002-0232-1284
dc.identifier.urihttps://doi.org/10.4274/mjima.galenos.2022.2022.26
dc.identifier.urihttps://hdl.handle.net/20.500.12899/5105
dc.identifier.volume11
dc.identifier.wosWOS:000964556200001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofMediterranean Journal of Infection Microbes and Antimicrobials
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260612
dc.subjectSars-Cov-2
dc.subjectViral Load
dc.subjectLymphopenia
dc.titleRelationship Between Viral Load and Laboratory Values and Radiological Findings in Patients with COVID-19
dc.typeArticle

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