The importance of urotensin II level in the diagnosis of acute mesenteric ischemia

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dc.contributor.authorÇAY, Ferhat ÇAY
dc.contributor.authorÇETİNKAYA, HASAN BASRİ
dc.contributor.authorDURAN, ALİ
dc.contributor.authorKULOĞLU, TUNCAY
dc.contributor.authorkanat, burhan hakan
dc.contributor.authorUstundag, Bilal
dc.date.accessioned2025-10-24T18:03:59Z
dc.date.available2025-10-24T18:03:59Z
dc.date.issued2022
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractAim: This study was conducted to investigate the diagnostic importance of Urotensin II (UT-II) levels, which cause vasodilation as a compensation mechanism in the early phase of Acute Mesenteric Ischemia (AMI). For this purpose, human plasma urotensin was studied for the first time in the literature for the early diagnosis of mesenteric ischemia. Material and Method: The study consisted of 60 patients. The patients were divided into three groups: Group 1: group with mesenteric ischemia (n: 20); Group 2: group with abdominal pain and with no mesenteric ischemia (n: 20); Group 3: control group with no complaints (n: 20). The blood samples were taken from the patients through peripheral venous access, and Urotensin II (UT-II), Aspartate Aminotransferase (AST), Alkaline phosphatase (ALP), Lactate, and D-dimer levels were measured. Results: While a significant increase was found between Group1 and Group 2 and between Group1 and Group3 in terms of UT-II values (p0.05). A significant increase was found between Group1 and Group2 and between Group1 and Group3 regarding AST values (p0.05). There was a significant increase between Group1 and Group3 in terms of D-dimer values (p0.05). There was no significant difference between the groups concerning ALP and Lactate values (P>0.05). Conclusion: It was concluded that UT-II could be used in the diagnosis of AMI but that there was a need for comprehensive studies investigating the changes in ischemia time-related UT-II serum levels.
dc.identifier.doi10.38053/acmj.1025305
dc.identifier.endpage63
dc.identifier.issn2718-0115
dc.identifier.issue1
dc.identifier.startpage59
dc.identifier.trdizinid1243259
dc.identifier.urihttps://doi.org/10.38053/acmj.1025305
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1243259
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2578
dc.identifier.volume4
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofAnatolian Current Medical Journal
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzTR-Dizin_20251023
dc.subjectD-dimer
dc.subjectAcute Mesenteric Ischemia
dc.subjectUrotensin-II
dc.titleThe importance of urotensin II level in the diagnosis of acute mesenteric ischemia
dc.typeArticle

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