Synthesis of new anthraquinone compounds and evaluation of their considerable xanthine oxidase inhibitory activities

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dc.contributor.authorParladi, Ufuk
dc.contributor.authorYilmaz, Ulku
dc.contributor.authorNoma, Samir Abbas Ali
dc.contributor.authorAtes, Burhan
dc.contributor.authorKucukbay, Hasan
dc.date.accessioned2026-06-19T06:38:03Z
dc.date.available2026-06-19T06:38:03Z
dc.date.issued2022
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractA series of anthraquinone derivatives (1-11) was prepared using alkyl halides, quinizarin, and danthron. The structural analysis of new compounds was carried out by 1H, 13C NMR, IR, and UV-Vis spectroscopic techniques. Xanthine oxidase inhibitory activities of compounds were measured using allopurinol as a standard. Inhibition abilities were identified by measuring the uric acid formation at 294 nm at 37 degrees C. According to the IC50 values of the compounds, it was observed that all the compounds in the group had higher inhibition values than allopurinol.
dc.identifier.doi10.24820/ark.5550190.p011.810
dc.identifier.issn1551-7004
dc.identifier.issn1551-7012
dc.identifier.orcid0000-0002-2806-4781
dc.identifier.orcid0000-0002-7180-9486
dc.identifier.scopus2-s2.0-85152746666
dc.identifier.scopusqualityQ4
dc.identifier.urihttps://doi.org/10.24820/ark.5550190.p011.810
dc.identifier.urihttps://hdl.handle.net/20.500.12899/5334
dc.identifier.wosWOS:000891399000001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherArkat Usa Inc
dc.relation.ispartofArkivoc
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260612
dc.subjectAnthraquinone Derivative
dc.subjectQuinizarin
dc.subjectDanthron
dc.subjectXanthine Oxidase
dc.subjectInhibition
dc.titleSynthesis of new anthraquinone compounds and evaluation of their considerable xanthine oxidase inhibitory activities
dc.typeArticle

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