Relationship between C-reactive protein/albumin ratio and lactate/albumin ratio and mortality in traumatic brain injury

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dc.contributor.authorOterkus, Mesut
dc.contributor.authorKuşderci, Hatice
dc.contributor.authorAkdeniz, Sevda
dc.contributor.authorGenc, Caner
dc.contributor.authorKayıkçi, Ebru
dc.date.accessioned2026-06-19T06:29:53Z
dc.date.available2026-06-19T06:29:53Z
dc.date.issued2025
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractWe aimed to evaluate whether C-Reactive Protein/Albumin Ratio (CAR) and Lactate/Albumin ratio (LAR), which include acute phase reactants that are indicators of secondary brain injury processes such as inflammatory process, cytokine release, and hypoxia that develop after primary injury, are predictors of mortality in patients with traumatic brain injury (TBI). Patients who were admitted to the emergency department with a diagnosis of traumatic brain injury and stayed in the intensive care unit for more than 24 hours were included in the study. It was conducted by scanning the retrospective records of patients diagnosed with TBI between January 2022 and December 2023 in our hospital. As a result of our study, acute physiology and chronic health assessment II (APACHE II) and Injury Severity Score (ISS) were independent risk factors for mortality in TBI, while CAR and LAR were not independent variables in terms of mortality. Similar findings were valid for Glasgow Outcome Score (GOS). In addition, in patients who died; LAR, hypertension, high APACHE II score, low Glasgow Coma Scale (GCS), high ISS, mechanical ventilation requirements vasopressor requirements at first admission to intensive care, high lactate level, and low albumin levels were meaningful of the results. APACHE II and ISS were independent risk factors for mortality in TBI, while CAR and LAR were not independent variables in terms of mortality. Similar findings were valid for GOS. In addition, LAR levels were significantly higher in patients with ex. These results show us that LAR may be a parameter in mortality prediction.
dc.identifier.doi10.5455/medscience.2025.02.035
dc.identifier.endpage630
dc.identifier.issn2147-0634
dc.identifier.issue3
dc.identifier.startpage625
dc.identifier.trdizinid1344925
dc.identifier.urihttps://doi.org/10.5455/medscience.2025.02.035
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1344925
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4804
dc.identifier.volume14
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR_20260612
dc.subjectKlinik Nöroloji
dc.titleRelationship between C-reactive protein/albumin ratio and lactate/albumin ratio and mortality in traumatic brain injury
dc.typeArticle

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