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    Demographic, Sociocultural, and Time-Related Patterns of Violent Suicide Attempts
    (Int Scientific Information, Inc, 2025) Cumaoglu, Mustafa Oguz; Vural, Abdussamed; Dolanbay, Turgut; Dogan, Mustafa; Sekme, Sabri
    Background: Violent suicide attempts (VSAs), characterized by high-lethality methods such as hanging, firearms, and sharpobject injuries, are a significant public health concern. While VSAs are widespread globally, research on their associated factors remains limited. This study investigated demographic, sociocultural, and environmental factors influencing VSAs in Turkey's southern region, emphasizing time-related and seasonal patterns, to guide public health strategies. Material/Methods: Data were retrospectively collected from 86 VSA patients admitted to Nigde University Hospital between January 1 and December 31, 2023. Parameters assessed included demographics, marital status, education, psychiatric history, suicide methods, time of day, weekday trends, and seasonal environmental factors like temperature, precipitation, and wind speed. Statistical analyses revealed meaningful associations between sociodemographic characteristics, clinical features, and environmental factors and patterns of violent suicide attempts. Results: VSAs were more frequent among men, single people, and divorced individuals. Gender differences emerged in suicide methods: men predominantly used hanging and firearms, while women favored sharp objects. Psychiatric disorders were significantly less common among married individuals compared to single people and divorcees. VSAs were more prevalent on weekdays, peaking in the morning, with fatality rates highest in the afternoon. Seasonal analysis revealed spring as the peak period for VSAs, correlated with higher precipitation and wind speeds. Conclusions: The findings show the role of demographic, psychiatric, and environmental factors in VSA patterns. High-risk groups include single and divorced individuals and those with psychiatric disorders. Tailored interventions addressing seasonal and time-related patterns and enhancing support networks could mitigate VSA risks. Improved mental health services and targeted public health policies are essential for effective suicide prevention.
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    Metabolic risk factors associated with premature myocardial infarction in adults ≤ 35 years: a case-control study
    (Bmc, 2026) Vural, Abdussamed; Dolanbay, Turgut; Cumaoglu, Mustafa Oguz; Elbasan, Zafer; Yuceer, Omer; Sekme, Sabri
    Background Acute myocardial infarction (AMI) in very young adults (<= 35 years) represents a distinct clinical entity with limited evidence. This study aimed to characterize metabolic risk factors differentiating young AMI patients from clinic-based controls. Methods This single-center retrospective case-control study included 62 consecutive young adults (aged 18-35 years) with confirmed AMI and 60 clinic-based controls selected from cardiology outpatient clinics during the same study period. Controls were selected using age (+/- 2 years) and sex restrictions to ensure group-level comparability with the AMI cohort. Metabolic parameters, including body mass index (BMI), LDL cholesterol, and blood glucose, were compared between groups. Effect sizes (Cohen's d) were calculated to assess clinical significance. Multivariable logistic regression was performed to identify independent predictors of AMI. Correlation analyses (Pearson or Spearman, as appropriate) were performed to examine relationships between metabolic markers. Results Young AMI patients demonstrated a significantly more unfavorable metabolic profile than controls: median BMI (26.5 vs. 23.9 kg/m & sup2;, p < 0.001), LDL cholesterol (136.5 vs. 108.0 mg/dL, p = 0.002), and blood glucose (120.0 vs. 95.0 mg/dL, p < 0.001). All three metabolic parameters showed large effect sizes (d > 1.0), indicating clinically substantial differences. In multivariable analysis, BMI (adjusted OR 1.28 per kg/m & sup2;, 95% CI 1.08-1.52), LDL cholesterol (adjusted OR 1.14 per 10 mg/dL, 95% CI 1.01-1.29), and blood glucose (adjusted OR 1.16 per 10 mg/dL, 95% CI 1.05-1.29) remained independently associated with AMI risk. LDL cholesterol showed a statistically significant, albeit weak, positive association with peak troponin levels (rho = 0.296, p = 0.020). Among AMI cases, STEMI patients exhibited higher acute glucose levels than NSTEMI patients (p = 0.004). Conclusion Very young adults (<= 35 years) with AMI exhibit markedly elevated BMI, LDL cholesterol, and glucose levels compared to age- and sex-comparable controls with large effect sizes supporting clinical significance. Multivariable analysis confirmed independent associations for all three metabolic parameters. These traditional modifiable risk factors continue to be strongly associated with early myocardial infarction, emphasizing the importance of aggressive metabolic screening and early prevention strategies in very young populations.