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    Early-life endurance sports lowers frailty and falls in former male athletes
    (Nature Portfolio, 2025) Bas, Keziban Gamze; Singin, Rabia Hurrem Ozdurak; Denizci, Tuba
    The long-term impact of professional endurance sports on frailty and fall risk in older age remains underexplored. This study examined frailty, physical activity (PA), and health outcomes in older men with and without a history of professional endurance sports. We assessed 200 men aged 60-85 years, 100 former professional endurance athletes (For-A) with >= 5 years of competitive experience and 100 age-matched non-athletes (Non-A). Frailty was evaluated using the Frailty Assessment Screening Tool (FAST), PA with the International PA Questionnaire-Short Form, quality of life (QoL) perception via self-report, and falls/hospitalizations via examination. Group differences were tested with Independent t-tests, Mann-Whitney U, and chi-square, while ANCOVA and logistic regression were employed to adjust for current PA. For-A showed lower frailty prevalence (24% vs. 68%, p = 0.001), higher PA (2385 vs. 299 MET-min/week, p = 0.001), better QoL (median 7 vs. 5, p = 0.001), fewer falls (OR = 0.023, 95% CI [0.004, 0.127], p < 0.001), and a non-significant reduction in hospitalizations (OR = 0.414, 95% CI [0.142, 1.202], p = 0.105) in the past year compared to Non-A. Frailty (p = 0.003) and falls (p < 0.001) remained significantly lower in For-A after adjustment for current PA (p = 0.003), but hospitalization differences attenuated. Early-life endurance training is associated with reduced frailty and potentially lower fall risk. While psychological health and hospitalization outcomes appear more dependent on current activity, the potential benefits for mobility, physical performance, continence, and memory suggest the importance of structured youth sports in supporting healthy and resilient aging. Longitudinal studies with diverse populations and objective measures are needed to confirm causality.
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    Quality and safety of youtube videos on epilepsy-specific exercises: A systematic analysis using a novel evaluation tool
    (W B Saunders Co Ltd, 2026) Gonulal, Yakup; Denizci, Tuba; Yesilkaya, Mehmetcan; Agascioglu, Eda; Aykac, Serdar; Singin, Rabia Hurrem Ozdurak
    Objective: Exercise benefits people with epilepsy (PWE) by reducing seizure frequency, improving quality of life, and fostering social participation. YouTube, a popular platform for health information, hosts numerous exercise videos for PWE, yet their quality, reliability, and safety remain unevaluated. This study aimed to evaluate the quality, reliability, and engagement of YouTube videos on epilepsy-specific exercises using the novel Epilepsy Content Evaluation (ECE) tool, alongside DISCERN, JAMA, and Global Quality Score (GQS). Method: A systematic search conducted on July 22, 2025, identified 45 English-language YouTube videos, which were independently evaluated by two neurologists using the ECE, DISCERN, JAMA, and GQS tools. Video characteristics, publisher sources, and engagement metrics were analyzed. Results: Most videos (53.3%) were rated low quality (ECE score 0-7), with only one (2.2%) achieving high quality (ECE score 12-15). The Safety and Risk Management subdomain scored lowest (median: 2, IQR: 1.25), reflecting inadequate attention to seizure triggers and supervision. Athlete-targeted videos outperformed general-population videos in quality (p < 0.05). View counts negatively correlated with ECE scores (r = -0.375 to -0.712, p < 0.05). ECE demonstrated strong convergent validity with DISCERN (Phi = 0.606, p = 0.035). Conclusion: In conclusion, most YouTube videos on epilepsy-specific exercises lack clinical reliability and safety guidance, posing potential risks for PWE. The ECE tool effectively identifies these deficiencies, enabling clinicians to recommend ILAE-aligned videos to enhance patient safety. Curated, evidence-based digital resources could empower millions of PWE to engage in safe physical activity, reducing stigma and improving health outcomes.