Clinical Implications of Post-Earthquake Environmental Exposures in Children with Allergic Diseases

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dc.contributor.authorKaplan, Fatih
dc.contributor.authorKurnaz Kaplan, Bilge
dc.contributor.authorArikanoglu, Emrullah
dc.contributor.authorGulyuz, Abdulgani
dc.date.accessioned2026-06-19T06:37:43Z
dc.date.available2026-06-19T06:37:43Z
dc.date.issued2026
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractHighlights What are the main findings? Post-earthquake environmental exposures were associated with worsening disease control in children with allergic diseases. Prolonged residence in temporary housing and exposure to demolition-related dust were independently associated with clinical deterioration, particularly among children with asthma. What are the implications of the main findings? Children with chronic allergic diseases should be considered a vulnerable population in post-disaster settings. Dust-control measures, air-quality monitoring, and improved living conditions in temporary housing may help reduce post-disaster worsening of allergic diseases.Highlights What are the main findings? Post-earthquake environmental exposures were associated with worsening disease control in children with allergic diseases. Prolonged residence in temporary housing and exposure to demolition-related dust were independently associated with clinical deterioration, particularly among children with asthma. What are the implications of the main findings? Children with chronic allergic diseases should be considered a vulnerable population in post-disaster settings. Dust-control measures, air-quality monitoring, and improved living conditions in temporary housing may help reduce post-disaster worsening of allergic diseases.Abstract Background/Objectives: Environmental changes following large-scale natural disasters may influence the clinical course of chronic diseases. However, the impact of post-earthquake environmental exposures on pediatric allergic diseases remains insufficiently studied. To evaluate the association between post-earthquake environmental exposures and disease control in children with allergic diseases. Methods: This retrospective longitudinal cohort study included 528 children with previously diagnosed asthma, allergic rhinitis, or atopic dermatitis who were followed in a tertiary pediatric allergy center in Malatya, T & uuml;rkiye. Clinical assessments performed before the 6 February 2023 Kahramanmara & scedil; earthquakes (T0) were compared with follow-up evaluations conducted 6-12 months after the earthquake (T1). Environmental exposures assessed during the post-earthquake period included prolonged residence in temporary housing, demolition-related dust exposure, and elevated ambient particulate matter levels. Clinical deterioration was defined using disease-specific indicators (decline in ACT/cACT score or treatment step escalation for asthma, increase in TNSS for allergic rhinitis, and increase in SCORAD for atopic dermatitis). Multivariable logistic and linear regression models were used to evaluate associations between environmental exposures and clinical outcomes. Results: Clinical deterioration was observed in 219 children (41.5%). Prolonged residence in temporary housing for >= 6 months (aOR 2.1, 95% CI 1.2-3.9, p = 0.01) and exposure to demolition-related dust (aOR 1.9, 95% CI 1.1-3.5, p = 0.02) were independently associated with clinical deterioration. Among children with asthma, both prolonged temporary housing (adjusted beta -1.84, p = 0.002) and demolition-related dust exposure (adjusted beta -1.39, p = 0.018) were associated with worsening asthma control. Conclusions: Post-earthquake environmental exposures, particularly prolonged residence in temporary housing and demolition-related dust exposure, were associated with worsening control of pediatric allergic diseases. These findings highlight the importance of environmental health considerations in disaster response and long-term management of children with chronic allergic conditions.
dc.identifier.doi10.3390/jcm15082875
dc.identifier.issn2077-0383
dc.identifier.issue8
dc.identifier.pmid42074687
dc.identifier.scopus2-s2.0-105037409386
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/jcm15082875
dc.identifier.urihttps://hdl.handle.net/20.500.12899/5189
dc.identifier.volume15
dc.identifier.wosWOS:001749857400001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMdpi
dc.relation.ispartofJournal of Clinical Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260612
dc.subjectEarthquake
dc.subjectPediatric Allergic Diseases
dc.subjectAsthma
dc.subjectEnvironmental Exposure
dc.subjectParticulate Matter
dc.subjectTemporary Housing
dc.subjectDemolition Dust
dc.subjectDisease Control
dc.titleClinical Implications of Post-Earthquake Environmental Exposures in Children with Allergic Diseases
dc.typeArticle

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