Can evaluating adrenal glands in computed tomography contribute to predicting the prognosis of hospitalized COVID-19 patients?

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dc.contributor.authorIlgar, M.
dc.contributor.authorUnlu, S.
dc.contributor.authorAkcicek, M.
dc.date.accessioned2026-06-19T06:41:23Z
dc.date.available2026-06-19T06:41:23Z
dc.date.issued2022
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractOBJECTIVE: The novel coronavirus disease 2019 (COVID-19) may affect the adrenal glands. Therefore, it is important to evaluate the morphologic appearance of the adrenal glands by thorax computed tomography (CT). On CT scans, stranding in peripheral fatty tissue with enlarged adrenal glands may indicate signs of adrenal infarction (SAI). The present study aimed to evaluate the incidence of SAI and determine whether this finding may contribute to predictions of the prognosis of COVID-19. PATIENTS AND METHODS: A total of 343 patients who had been hospitalized at Malatya Training and Research Hospital between September 1 and 30, 2020, with a diagnosis of COVID-19 were enrolled in this study. All patients underwent thorax CT scans that included their adrenal glands. RESULTS: Of the enrolled patients, 16.0% had SAI. Moreover, 41.8% of patients with SAI and 15.3% of patients without SAI were treated in the Intensive Care Unit (ICU). Patients with SAI had a significantly higher rate of ICU admission (p < 0.001). Mortality rates were also significantly higher among patients with SAI than those without p < 0.001). CONCLUSIONS: In this study, it was found that COVID-19 patients with SAI may have a poorer prognosis. More comprehensive studies are needed on this subject, but the present study may provide helpful preliminary information in terms of prognosis.
dc.identifier.endpage304
dc.identifier.issn1128-3602
dc.identifier.issue1
dc.identifier.orcid0000-0001-7535-0812
dc.identifier.orcid0000-0002-0232-1284
dc.identifier.pmid35049009
dc.identifier.scopus2-s2.0-85123654877
dc.identifier.scopusqualityN/A
dc.identifier.startpage298
dc.identifier.urihttps://hdl.handle.net/20.500.12899/6223
dc.identifier.volume26
dc.identifier.wosWOS:000745985100012
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review for Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20260612
dc.subjectCovid-19
dc.subjectComputed Tomography
dc.subjectAdrenal Gland
dc.titleCan evaluating adrenal glands in computed tomography contribute to predicting the prognosis of hospitalized COVID-19 patients?
dc.typeArticle

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