Correlation between iron stores and QTc dispersion in chronic ambulatory peritoneal dialysis patients

Basit Öğe Kaydı
dc.authoridErdemli, Haci Kemal/0000-0002-3399-4676|Duranay, Murat/0000-0002-2893-4484
dc.contributor.authorBavbek, Nuket
dc.contributor.authorYilmaz, Hakki
dc.contributor.authorErdemli, Haci Kemal
dc.contributor.authorSelcuki, Yusuf
dc.contributor.authorDuranay, Murat
dc.contributor.authorAkcay, Ali
dc.date.accessioned2025-10-24T18:09:44Z
dc.date.available2025-10-24T18:09:44Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractAim: We aimed to investigate the QT dispersion and corrected QT (QTc) dispersion which are suggested as the signals of ventricular arrhythmias, in patients on maintenance CAPD and to evaluate the correlation between iron stores and these electrocardiographic parameters. Materials and method: Fifty-eight patients on maintenance CAPD and 19 healthy age- and sex-matched adults without cardiac disease were included. The PD patients were divided into two groups according to whether their computerized measurements of QTc dispersion were longer than 65 ms. Results: Although QT interval was statistically significantly shorter in control group (34 +/- 28 vs. 43 +/- 34 ms; p<0.05), there was no significant difference in regards to the QTc, QT dispersion and QTc dispersion between two groups. PD patients with QTc dispersion longer than 65 ms had higher levels of serum ferritin (p = 0.038) and transferrin saturation (TSAT; p = 0.022) than the others. QTc dispersion were positively correlated with ferritin (r = 0.469, p<0.01) and TSAT (r = 0.430, p<0.01) in CAPD patients. Conclusion: Although prolonged QTc, QT dispersion and QTc dispersion were suggested as the markers of ventricular arrhythmias we did not find any significant difference in regards to these parameters between control patients and CAPD patients. But the high body iron stores in these patients increase the risk of increased QT dispersion. The concern over iron overload in dialysis patients is not only because of its oxidative toxicity, but also its precipitation of arrhythmias, which may be measured by the surrogate marker of QTc dispersion.
dc.identifier.doi10.3109/0886022X.2013.836750
dc.identifier.endpage190
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue2
dc.identifier.pmid24059284
dc.identifier.scopus2-s2.0-84896702128
dc.identifier.scopusqualityQ2
dc.identifier.startpage187
dc.identifier.urihttps://doi.org/10.3109/0886022X.2013.836750
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3784
dc.identifier.volume36
dc.identifier.wosWOS:000333168000006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherInforma Healthcare
dc.relation.ispartofRenal Failure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectCAPD; QTc; QT dispersion; QTc dispersion
dc.titleCorrelation between iron stores and QTc dispersion in chronic ambulatory peritoneal dialysis patients
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu