New hemostatic agent: the effect of Ankaferd Blood Stopper on healing wounds in experimental skin incision model

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dc.authoridYENIDUNYA, SIBEL/0000-0002-5645-6301
dc.contributor.authorYuce, Serdar
dc.contributor.authorCandirli, Celal
dc.contributor.authorYenidunya, Sibel
dc.contributor.authorMuslu, Bunyamin
dc.date.accessioned2025-10-24T18:09:50Z
dc.date.available2025-10-24T18:09:50Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractAim: To conduct a histopathological evaluation of the effects of Ankaferd Blood Stopper (ABS) on healing wounds in a rabbit skin incision model. Materials and methods: Incisions were performed on the backs of rabbits. The first incision was allowed to undergo normal secondary healing. ABS (1 mL) was applied to the second incision, which was subsequently allowed to undergo secondary healing. The third incision was sutured. ABS (1 mL) was applied to the fourth incision, which was subsequently sutured. During the wound healing period, the histopathologic signs of ulceration, inflammation, the proliferative phase, and the extent of early remodeling were comparatively evaluated by performing biopsies on days 5, 10, and 30. Results: For all of the ABS-treated wounds, the appearance of the cavities during the early stage and the disappearance of the cavities during the late stage were observed. In addition, on days 5-10, the inflammatory granulation tissue in the ABS-treated wounds was less than in the normal wounds. By day 30, all of the wounds had achieved the same symptomatic state. Conclusion: As ABS does not exert any negative effects on wound healing, this agent is a secure and effective method for achieving hemostasis.
dc.identifier.doi10.3906/sag-1302-92
dc.identifier.endpage294
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue2
dc.identifier.pmid25536739
dc.identifier.scopus2-s2.0-84892419676
dc.identifier.scopusqualityQ1
dc.identifier.startpage288
dc.identifier.trdizinid213060
dc.identifier.urihttps://doi.org/10.3906/sag-1302-92
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/213060
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3859
dc.identifier.volume44
dc.identifier.wosWOS:000329790100020
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal Of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectHemostatic agent; wound healing; skin incision
dc.titleNew hemostatic agent: the effect of Ankaferd Blood Stopper on healing wounds in experimental skin incision model
dc.typeArticle

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