The effectiveness of local steroid injection after internal urethrotomy to avoid recurrence

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dc.authoridYILDIRIM, MEHMET/0000-0003-4768-4537|Kaynar, Mehmet/0000-0002-6957-9060
dc.contributor.authorYildirim, Mehmet Erol
dc.contributor.authorKaynar, Mehmet
dc.contributor.authorOzyuvali, Ekrem
dc.contributor.authorBadem, Huseyin
dc.contributor.authorCakmak, Muzaffer
dc.contributor.authorKosem, Bahadir
dc.contributor.authorCimentepe, Ersin
dc.date.accessioned2025-10-24T18:09:57Z
dc.date.available2025-10-24T18:09:57Z
dc.date.issued2015
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: Local steroid injection to the stricture region after internal urethrotomy (IU) is a promising technique to avoid the recurrence, although the effectiveness and safety of this technique is still controversial. We aimed to determine the efficacy and safety of local steroids as applied with the IU procedure. Material-Method: A total of 83 patients data with urethral stricture in men were examined retrospectively. Patients classified in two groups who had steroid injection with internal urethrotomy or not. Metil prednisolone 40 mg was injected with transurethral injection needle in the stricture region at the 5, 7 and 12 o'clock sites at the same session with internal urethrotomy. Procedure was considered successful if patient did not report any voiding difficulty and maximum flow rate > 15 mL/second for a voided volume of at least 150 mL after removal of the catheter. Patient's age, time to recurrence, previous recurrences were evaluated. Results: The mean age was 56.4 (18-83) years. Of those patients 33/83 had recurrent stenosis. Nineteen out of these 33 recurrent stenosis patients were treated with local steroid injection and 14/33 had no injection. Only two patients of the steroid treated group had recurrence. Despite that 12 patients had recurrence in the steroid non-treated group. Also the primary stenosis patients showed no recurrence at the steroid+ IU group. Conclusions: The use of local steroids with IU seems to decrease the high stricture recurrence rate following IU. When local steroids were administered with complementary intention, the disease control outcomes are encouraging. Further robust comparative effectiveness studies are now required.
dc.identifier.doi10.4081/aiua.2015.4.295
dc.identifier.endpage298
dc.identifier.issn1124-3562
dc.identifier.issn2282-4197
dc.identifier.issue4
dc.identifier.pmid26766801
dc.identifier.scopus2-s2.0-84975041692
dc.identifier.scopusqualityQ3
dc.identifier.startpage295
dc.identifier.urihttps://doi.org/10.4081/aiua.2015.4.295
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3890
dc.identifier.volume87
dc.identifier.wosWOS:000440260900007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPagepress Publ
dc.relation.ispartofArchivio Italiano Di Urologia E Andrologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectUrethral stricture; Internal urethrotomy; Steroid; Recurrence
dc.titleThe effectiveness of local steroid injection after internal urethrotomy to avoid recurrence
dc.typeArticle

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