In Vitro Efficacy of Ceftazidime-Avibactam on Carbapenem-Resistant Pseudomonas aeruginosa Isolates

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dc.contributor.authorMansur, Ahmet
dc.contributor.authorGündüz, Ayten
dc.date.accessioned2025-10-24T17:59:19Z
dc.date.available2025-10-24T17:59:19Z
dc.date.issued2025
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractPseudomonas aeruginosa is the main Pseudomonas species causing hospital infections. Ceftazidime-avibactam (CZA) is a new beta-lactam/beta-lactamase inhibitor combination effective against carbapenem-resistant P. aeruginosa isolates. The aim of this study was to evaluate the in vitro activity of CZA against carbapenem-resistant P. aeruginosa isolates. In hospitalized patient culture samples, 190 isolates that were evaluated as significant growth and identified as P. aeruginosa with the Vitek 2 Compact automated system (BioMérieux, France) and determined as imipenem resistant (? 8 mg/L) and meropenem resistant (? 16 mg/L)with the same system were included in the study. 88% (167/190) of P. aeruginosa strains were isolated from patients in intensive care units and 78% (148/190) from respiratory tract samples. CZA activity was studied with disk diffusion test (10-4 µg disk) and zone diameters
dc.identifier.doi10.71133/anatphar.1630540
dc.identifier.endpage52
dc.identifier.issn2980-0463
dc.identifier.issue1
dc.identifier.startpage48
dc.identifier.urihttps://doi.org/10.71133/anatphar.1630540
dc.identifier.urihttps://hdl.handle.net/20.500.12899/2038
dc.identifier.volume4
dc.language.isoen
dc.publisherInonu University
dc.relation.ispartofAnatolian Journal of Pharmaceutical Sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzDergiPark_20251023
dc.subjectBacteriology
dc.subjectBakteriyoloji
dc.titleIn Vitro Efficacy of Ceftazidime-Avibactam on Carbapenem-Resistant Pseudomonas aeruginosa Isolates
dc.typeArticle

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