Galectin-1 as a potential diagnostic biomarker in polycystic ovary syndrome

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dc.contributor.authorAladag, H.
dc.contributor.authorKiran, T. R.
dc.contributor.authorInceoglu, F.
dc.contributor.authorYildirim, E.
dc.contributor.authorYaprak, B.
dc.contributor.authorKarabulut, A. B.
dc.contributor.authorAladag, M.
dc.date.accessioned2026-06-19T06:41:27Z
dc.date.available2026-06-19T06:41:27Z
dc.date.issued2023
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractOBJECTIVE: This study was aimed at comparing the routine laboratory pa-rameters and Galectin-1 levels of control and polycystic ovarian syndrome patients.PATIENTS AND METHODS: 88 patients di-agnosed with polycystic ovary syndrome and 88 healthy controls were considered for the study. Age groups of the patients ranged from 18 to 40. Serum TSH, Beta HCG, glucose, insulin, HO-MA-IR, Hb1A1c, triglyceride, total cholesterol, LDL FSH, LH, E2, prolactin, testosterone, SHBG, DHESO4, HDL, Gal-1 levels were analyzed for each subject.RESULTS: FSH, LH, LH/FSH, E2, prolactin, testosterone, SHBG, DHESO4, HDL and Gal -1 values of the subjects included in the study were statistically significantly different between the groups (p<0.05). Gal-1 and DHESO4 showed a strong positive connection (p=0.05). The sen-sitivity of Gal-1 level in PCOS patients was cal-culated as 0.997 and specificity as 0.716.CONCLUSIONS: High levels of Gal-1 in PCOS patients suggest that it increases due to overex-pression in response to inflammation.
dc.identifier.endpage2551
dc.identifier.issn1128-3602
dc.identifier.issue6
dc.identifier.orcid0000-0001-7937-4141
dc.identifier.pmid37013772
dc.identifier.scopus2-s2.0-85151707281
dc.identifier.scopusqualityN/A
dc.identifier.startpage2543
dc.identifier.urihttps://hdl.handle.net/20.500.12899/6246
dc.identifier.volume27
dc.identifier.wosWOS:000971936600039
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review for Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20260612
dc.subjectPolycystic Ovary Syndrome
dc.subjectGal-1
dc.subjectDheso4
dc.subjectDiabe-Tes
dc.subjectInflammation
dc.subjectObesity
dc.titleGalectin-1 as a potential diagnostic biomarker in polycystic ovary syndrome
dc.typeArticle

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