A Needle-Free Injection System (INJEX™) with lidocaine for epidural needle insertion: A randomized controlled trial

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dc.contributor.authorGozdemir, Muhammet
dc.contributor.authorDemircioglu, Ruveyda Irem
dc.contributor.authorKarabayirli, Safinaz
dc.contributor.authorSert, Huseyin
dc.contributor.authorMuslu, Bunyamin
dc.contributor.authorUsta, Burhanettin
dc.contributor.authorYazici, Ummugulsum
dc.date.accessioned2025-10-24T18:09:34Z
dc.date.available2025-10-24T18:09:34Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjectives: Local anesthetic infiltration is also a process of a painful process itself. INJEX (TM) technology, known as Needle-free drug delivery system, was designed for reducing the pain associated with cutaneous procedures. We conducted a prospective, randomized trial to evaluate the application of lidocaine with INJEX (TM) system and 27-gauge needle. Methods: A total of 60 consecutive patients were allocated to receive either INJEX group or 27-gauge needle group. Local anesthetic infiltration was applied two minutes before epidural needle insertion. Results: Mean VAS, at the time of local anesthetic injection was 0 for group I and 2 for group II. When the effect of epidural needle insertion was compared, the mean VAS score was one versus two for Group-I versus Group-II, respectively. Lidocaine applied with the INJEX (TM) system before epidural needle insertion significantly reduced the intensity of pain during that procedure and was least effective the lidocaine applied with the 27-gauge needle and patients felt less pain during at the time of local anesthetic injection in Group-I. Conclusion: Needle-free delivery of lidocaine is an effective, easy to-use and noninvasive method of providing local anesthesia for the epidural needle insertion.
dc.identifier.doi10.12669/pjms.323.9174
dc.identifier.endpage761
dc.identifier.issn1682-024X
dc.identifier.issue3
dc.identifier.pmid27375728
dc.identifier.startpage756
dc.identifier.urihttps://doi.org/10.12669/pjms.323.9174
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3708
dc.identifier.volume32
dc.identifier.wosWOS:000377706400047
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherProfessional Medical Publications
dc.relation.ispartofPakistan Journal Of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectNeedle Free; Injection; Local Anesthetic delivery; Technology
dc.titleA Needle-Free Injection System (INJEX™) with lidocaine for epidural needle insertion: A randomized controlled trial
dc.typeArticle

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