Effect of Underlying Infertility Factors on Second Trimester Serum Screening Results

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dc.contributor.authorKosus, Nermin
dc.contributor.authorKosus, Aydin
dc.contributor.authorDuran, Muzeyyen
dc.contributor.authorTurhan, Nilgun O.
dc.date.accessioned2025-10-24T18:10:16Z
dc.date.available2025-10-24T18:10:16Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractOBJECTIVE: To determine whether assisted reproductive technologies (ART) alone or an underlying cause of infertility has any effect on second trimester serum screening results. STUDY DESIGN: Second trimester serum screening results of ART pregnancies of women with polycystic ovary syndrome (IVF-P group) were compared with those of women who underwent ART dike to male factor infertility (IVF-M group) and of women who conceived spontaneously. RESULTS: Comparison of the groups for a-fetoprotein, beta-hCG, and beta-hCG multiples of the median (MoM) revealed a significant difference between the IVF-M and control groups. Comparison of groups for unconjugated estriol (uE(3)) and uE(3) MoM levels revealed a statistically significant difference between the IVF-P versus the control groups. CONCLUSION: It seems advisable to use a population of ART pregnancies, preferably divided by type of treatment and the etiology of the infertility, when establishing median curves for second trimester serum screening markers.
dc.identifier.endpage80
dc.identifier.issn0024-7758
dc.identifier.issn1943-3565
dc.identifier.issue1-2
dc.identifier.pmid24597291
dc.identifier.startpage76
dc.identifier.urihttps://hdl.handle.net/20.500.12899/4074
dc.identifier.volume59
dc.identifier.wosWOS:000330334800015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSci Printers & Publ Inc
dc.relation.ispartofJournal Of Reproductive Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectalpha-fetoprotein; human; Down's syndrome; estriol; HCG-beta; infertility; polycystic ovary syndrome; reproductive technology; assisted; screening; second trimester screening
dc.titleEffect of Underlying Infertility Factors on Second Trimester Serum Screening Results
dc.typeArticle

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