Bupivacaine-soaked absorbable gelatin sponges in caesarean section wounds: effect on postoperative pain, analgesic requirement and haemodynamic profile

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dc.authoridKaygusuz, Ikbal/0000-0002-5635-505X;
dc.contributor.authorSimavli, S.
dc.contributor.authorKaygusuz, I.
dc.contributor.authorKinay, T.
dc.contributor.authorBaylan, A. Akinci
dc.contributor.authorKafali, H.
dc.date.accessioned2025-10-24T18:09:02Z
dc.date.available2025-10-24T18:09:02Z
dc.date.issued2014
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractBackground: Pain is a common distressing adverse effect in the early postoperative period following caesarean section. The aim of this study was to investigate the effect on postoperative pain, analgesic requirement and haemodynamic profile of placing a suprafacial bupivacaine-soaked absorbable gelatin sponge in the caesarean section wound. Methods: A total of 164 healthy patients scheduled to undergo general anaesthesia for elective caesarean section were randomised to a study group (n=81) or a control group (n=83). In the study group, a bupivacaine-soaked absorbable gelatin sponge was placed subcutaneously in the caesarean section wound. Intramuscular diclofenac 75 mg was given to all patients at 8-h intervals during the first 24 h. Postoperatively, visual analogue scale pain scores, requirement for pethidine and diclofenac and changes in blood pressure and heart rate were compared between groups. Results: Pain scores were lower in the study group compared to the control group at all assessments (P <0.001). During the first eight hours after surgery, fewer patients in the study group required rescue pethidine compared with the control group (4 vs. 33, P <0.001). In the study group, total opioid and diclofenac consumption was lower (P <0.001), and blood pressure and heart rate were lower (P <0.001) compared to the control group. Conclusion: Suprafascial wound placement of a bupivacaine-soaked absorbable gelatin sponge improved postoperative analgesia and decreased opioid consumption following caesarean section. (C) 2014 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.ijoa.2014.07.004
dc.identifier.endpage308
dc.identifier.issn0959-289X
dc.identifier.issn1532-3374
dc.identifier.issue4
dc.identifier.pmid25281438
dc.identifier.scopus2-s2.0-84908339117
dc.identifier.scopusqualityQ2
dc.identifier.startpage302
dc.identifier.urihttps://doi.org/10.1016/j.ijoa.2014.07.004
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3434
dc.identifier.volume23
dc.identifier.wosWOS:000345203200002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Sci Ltd
dc.relation.ispartofInternational Journal Of Obstetric Anesthesia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20251023
dc.subjectGelatin sponge; Bupivacaine; Caesarean section; Postoperative pain
dc.titleBupivacaine-soaked absorbable gelatin sponges in caesarean section wounds: effect on postoperative pain, analgesic requirement and haemodynamic profile
dc.typeArticle

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