Factors affecting clinical pregnancy rates after IUI for the treatment of unexplained infertility and mild male subfertility

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dc.authoridKalem, Ziya/0000-0002-5435-2074|NAMLI KALEM, MUBERRA/0000-0002-2316-5495
dc.contributor.authorAtasever, Melahat
dc.contributor.authorKalem, Muberra Namli
dc.contributor.authorHatirnaz, Safak
dc.contributor.authorHatirnaz, Ebru
dc.contributor.authorKalem, Ziya
dc.contributor.authorKalaylioglu, Zeynep
dc.date.accessioned2025-10-24T18:10:08Z
dc.date.available2025-10-24T18:10:08Z
dc.date.issued2016
dc.departmentMalatya Turgut Özal Üniversitesi
dc.description.abstractObjective: The aim of the present retrospective study was to evaluate intrauterine insemination (IUI) clinical experiences and to define the variables for predicting success. Material and Methods: The present study was an observational trial performed in a private IVF center on subfertile couples who had applied for treatment between 2002 and 2012, in which the data of 503 IUI cases were retrospectively reviewed. Couples who had been diagnosed with unexplained and mild male subfertility were included. The primary outcome measure was the clinical pregnancy rate in an attempt to form a predictive model for the odds of a clinical pregnancy. Recorded parameters were used to determine the prediction model. Results: Utilizing univariate logistic regression analysis, clinical pregnancy was positively associated with the duration of infertility (OR=1.09, p=0.089), secondary infertility (OR=1.77, p=0.050), and +4 sperm motility after preparation (OR=1.03, p=0.091). Following an adjustment analysis involving a multivariate logistic regression, clinical pregnancy was still found to positively associate with secondary infertility (OR=2.51, p=0.008). Conclusion: IUI success in secondary infertile couples who were in the unexplained infertility and mild male subfertility groups was higher than that in primary infertile couples, and the chances of pregnancy increased as sperm numbers with +4 motility increased. It is difficult to concomitantly evaluate all these parameters and to determine a predictive parameter in IUI independent from other factors.
dc.identifier.doi10.5152/jtgga.2016.16056
dc.identifier.endpage138
dc.identifier.issn1309-0399
dc.identifier.issn1309-0380
dc.identifier.issue3
dc.identifier.pmid27651720
dc.identifier.scopus2-s2.0-84987650899
dc.identifier.scopusqualityQ3
dc.identifier.startpage134
dc.identifier.urihttps://doi.org/10.5152/jtgga.2016.16056
dc.identifier.urihttps://hdl.handle.net/20.500.12899/3983
dc.identifier.volume17
dc.identifier.wosWOS:000391064900005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofJournal Of The Turkish-German Gynecological Association
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20251023
dc.subjectIntrauterine insemination; unexplained infertility; male subfertility
dc.titleFactors affecting clinical pregnancy rates after IUI for the treatment of unexplained infertility and mild male subfertility
dc.typeArticle

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