Relieving the pressure: the effect of active carbon dioxide aspiration on postoperative pain after laparoscopic cholecystectomy
Küçük Resim Yok
Tarih
2026
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bmc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background Residual carbon dioxide (CO2) after laparoscopic cholecystectomy (LC) may contribute to early postoperative pain. Active aspiration of CO2 has been proposed as a simple adjunct, but large cohort data remain limited. Methods This non-randomized prospective cohort study included 270 patients undergoing LC between May 2025 and October 2025. Patients were allocated to either the active aspiration group (n = 135) or the passive evacuation group (n = 135). Pain was evaluated using the Visual Analog Scale (VAS) at 4 and 24 h. Statistical analyses included chi-square tests, independent and paired t-tests, and Pearson correlation. A priori power analysis determined that 266 patients (133 per group) were required (effect size d = 0.40, alpha = 0.05, power = 0.90). Results The aspiration group had significantly lower pain scores at both 4 h (3.48 +/- 1.08 vs. 5.30 +/- 1.60; p < 0.001) and 24 h (1.69 +/- 0.94 vs. 3.59 +/- 1.38; p < 0.001). Active aspiration was associated with lower pain scores at both time points (p < 0.001). Conclusion Active evacuation of residual CO2 was associated with lower postoperative pain scores following LC. Given the non-randomized design, causal inference is limited, and the findings should be interpreted cautiously.
Açıklama
Anahtar Kelimeler
Laparoscopic Cholecystectomy, Active Gas Aspiration, Carbon Dioxide Evacuation, Postoperative Pain, Visual Analog Scale
Kaynak
Bmc Surgery
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
26
Sayı
1
